Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 9/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23568458 | 0.80 | KDM4E (0.53) | CARM1PRMT6PRMT8KDM4EALDH1A1 | |
| SCHEMBL9875186 | 0.79 | CARM1 (0.70) | CARM1PRMT6PRMT8KDM4EALDH1A1 | |
| SCHEMBL20004363 | 0.77 | PYCR1 (0.57) | CARM1PRMT6PRMT8KDM4EALDH1A1 | |
| SCHEMBL17195529 | 0.76 | CARM1 (0.41) | CARM1PRMT6PRMT8KDM4EALDH1A1 | |
| SCHEMBL22856185 | 0.76 | KDM4E (0.41) | CARM1PRMT6PRMT8KDM4EALDH1A1 | |
| SCHEMBL5776237 | 0.76 | CYP2A6 (0.42) | CARM1PRMT6PRMT8KDM4EALDH1A1 | |
| SCHEMBL20004587 | 0.76 | PYCR1 (0.47) | CARM1PRMT6PRMT8KDM4EALDH1A1 | |
| SCHEMBL13052123 | 0.75 | TSHR (0.61) | CARM1PRMT6PRMT8KDM4EALDH1A1 | |
| SCHEMBL1472497 | 0.74 | NR1I2 (0.42) | KDM4EALDH1A1PYCR1HRH3TSHR | |
| SCHEMBL22537472 | 0.74 | PYCR1 (0.42) | CARM1PRMT6PRMT8KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | CARM1 458/4885PRMT6 2590/4885PRMT8 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.