Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.55 |
| ▸ | BCR | P11274 | 15/20 | 0.55 |
| ▸ | SRC | P12931 | 10/20 | 0.55 |
| ▸ | PRKCA | P17252 | 8/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | PRKCG | P05129 | 1/20 | 0.50 |
| ▸ | PRKCB | P05771 | 1/20 | 0.50 |
| ▸ | PRKCH | P24723 | 1/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.50 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
| ▸ | ABL2 | P42684 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774437 | 0.92 | ABL1 (0.62) | ABL1BCRSRCPRKCAPRKCD | |
| SCHEMBL5776974 | 0.85 | ABL1 (0.56) | ABL1BCRSRCPRKCAPRKCD | |
| SCHEMBL5775501 | 0.85 | ABL1 (0.55) | ABL1BCRPRKCAPDGFRBPDGFRA | |
| SCHEMBL5775711 | 0.80 | ABL1 (0.68) | ABL1BCRPRKCAPDGFRBPDGFRA | |
| SCHEMBL7475764 | 0.79 | JAK2 (0.71) | ABL1BCRSRCPRKCAPRKCD | |
| SCHEMBL4895446 | 0.77 | ABL1 (0.63) | ABL1BCRSRCPRKCAPRKCD | |
| Cyclohexane SCHEMBL5776808 | 0.77 | ABL1 (0.63) | ABL1BCRSRCPRKCAPRKCD | |
| SCHEMBL3123409 | 0.76 | ABL1 (0.82) | ABL1BCRSRCPRKCAPRKCD | |
| SCHEMBL4903264 | 0.75 | ABL1 (0.70) | ABL1BCRSRCPRKCAPRKCD | |
| SCHEMBL4905073 | 0.75 | ABL1 (0.67) | ABL1BCRSRCPRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395261-B1 | PYRIDYLPYRIMIDINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST PRION DISEASES | GPC BIOTECH AG (DE) | 2006-06-28 | — | — | EP | claimed |