Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.53 |
| ▸ | BCR | P11274 | 3/20 | 0.53 |
| ▸ | PRKCA | P17252 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 11/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4905681 | 0.85 | ABL1 (0.57) | ABL1BCRPRKCAALDH1A1SYK | |
| SCHEMBL5734023 | 0.79 | ABL1 (0.64) | ABL1BCRPRKCASYKPRKCD | |
| SCHEMBL5776913 | 0.77 | PDGFRA (0.47) | ABL1BCRPRKCASYKKDR | |
| SCHEMBL4901723 | 0.77 | ABL1 (0.64) | ABL1BCRPRKCAPRKCDSRC | |
| SCHEMBL4901606 | 0.75 | IKBKB (0.57) | ABL1BCRPRKCAALDH1A1SYK | |
| SCHEMBL4905854 | 0.75 | ABL1 (0.57) | ABL1BCRPRKCAALDH1A1SYK | |
| SCHEMBL4902412 | 0.75 | ABL1 (0.57) | ABL1BCRPRKCAALDH1A1SYK | |
| SCHEMBL5740498 | 0.75 | ABL1 (0.57) | ABL1BCRPRKCASYK | |
| SCHEMBL6041185 | 0.74 | CYP19A1 (0.58) | ABL1BCRPRKCAALDH1A1SYK | |
| SCHEMBL4900774 | 0.74 | ABL1 (0.59) | ABL1BCRPRKCASYKPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395261-B1 | PYRIDYLPYRIMIDINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST PRION DISEASES | GPC BIOTECH AG (DE) | 2006-06-28 | — | — | EP | claimed |