Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 7/20 | 0.47 |
| ▸ | ABL1 | P00519 | 6/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.47 |
| ▸ | BCR | P11274 | 3/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 5/20 | 0.45 |
| ▸ | KIT | P10721 | 3/20 | 0.45 |
| ▸ | ABL2 | P42684 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | GPR39 | O43194 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4902265 | 0.86 | ALDH1A1 (0.53) | PDGFRAABL1PDGFRBBCRPRKCA | |
| SCHEMBL7477243 | 0.80 | SYK (0.62) | PDGFRAABL1PDGFRBBCRPRKCA | |
| SCHEMBL4902031 | 0.79 | CCNT1 (0.50) | PDGFRAABL1PDGFRBBCRPRKCA | |
| SCHEMBL4903437 | 0.78 | PDGFRA (0.73) | PDGFRAABL1PDGFRBBCRPRKCA | |
| SCHEMBL5775770 | 0.78 | PDGFRA (0.53) | PDGFRAABL1PDGFRBBCRPRKCA | |
| SCHEMBL5778115 | 0.78 | ABL1 (0.67) | PDGFRAABL1PDGFRBBCRPRKCA | |
| SCHEMBL28434538 | 0.77 | PRKCA (0.53) | PDGFRAABL1PDGFRBBCRPRKCA | |
| SCHEMBL5777331 | 0.77 | ABL1 (0.53) | ABL1BCRPRKCASYKKDR | |
| SCHEMBL6041077 | 0.76 | ALDH1A1 (0.55) | PDGFRAABL1PDGFRBBCRPRKCA | |
| SCHEMBL4901214 | 0.76 | PDGFRA (0.64) | PDGFRAABL1PDGFRBBCRPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395261-B1 | PYRIDYLPYRIMIDINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST PRION DISEASES | GPC BIOTECH AG (DE) | 2006-06-28 | — | — | EP | claimed |