Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | WNT1 | P04628 | 8/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.48 |
| ▸ | GSK3B | P49841 | 6/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.36 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780655 | 0.86 | JAK3 (0.51) | JAK3WNT1DYRK1AGSK3BMAOA | |
| SCHEMBL5779730 | 0.84 | JAK3 (0.64) | JAK3MAOAMAOBCA2CA7 | |
| SCHEMBL5779732 | 0.84 | JAK3 (0.64) | JAK3MAOAMAOBCA2CA7 | |
| SCHEMBL5774553 | 0.79 | NPC1 (0.40) | NPC1RAB9AGAALMNAPKM | |
| SCHEMBL5779129 | 0.79 | PTK2 (0.39) | NPC1RAB9AGAALMNAPKM | |
| SCHEMBL5774952 | 0.79 | NPC1 (0.39) | NPC1RAB9AGAALMNAPKM | |
| SCHEMBL5776228 | 0.77 | RAB9A (0.55) | NPC1RAB9AGAALMNAPKM | |
| SCHEMBL14742652 | 0.77 | RAB9A (0.55) | NPC1RAB9AGAALMNAPKM | |
| Hydrochloric Acid SCHEMBL5778200 | 0.76 | RAB9A (0.57) | NPC1RAB9AGAALMNAPKM | |
| SCHEMBL5777456 | 0.76 | JAK3 (0.51) | JAK3WNT1DYRK1AGSK3BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | JAK3 4560/4885WNT1 479/4885DYRK1A 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.