Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557268 | 0.86 | FFAR4 (0.61) | NOTUMFFAR4ADRA1DADRA1AADRA1B | |
| SCHEMBL25845505 | 0.84 | GFER (0.55) | AKR1C3FFAR4USP2LMNAMAPT | |
| SCHEMBL4703338 | 0.83 | NOTUM (0.50) | NOTUMFFAR4USP2ADRA1DADRA1A | |
| SCHEMBL22657728 | 0.80 | ATM (0.51) | NOTUMFFAR4GPR119LMNAMAPT | |
| SCHEMBL25845507 | 0.79 | MAPT (0.60) | LMNAMAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL1024921 | 0.78 | FFAR4 (0.56) | FFAR4CHRM4 | |
| Hydrochloric Acid SCHEMBL8332331 | 0.78 | CKS1B (0.58) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL4505679 | 0.78 | ACHE (0.63) | ACHE | |
| SCHEMBL12154736 | 0.78 | ACHE (0.64) | AKR1C3ACHEL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL12903659 | 0.77 | NOTUM (0.64) | NOTUMGPR119USP2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641758-A2 | DIPHENYLPYRIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | Sanofi-Aventis (FR) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005000817-A2 | DIPHENYLPYRIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2005-01-06 | — | — | WO | disclosed |