Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.47 |
| ▸ | CD74 | P04233 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2975019 | 0.91 | CTSS (0.57) | CTSSCD74KCNK3ALDH1A1MEN1 | |
| SCHEMBL2976007 | 0.87 | CTSS (0.56) | CTSSCD74 | |
| SCHEMBL7099784 | 0.84 | CTSS (0.47) | CTSSCD74KCNK3 | |
| SCHEMBL2976436 | 0.81 | CTSS (0.58) | CTSSCD74KCNK3 | |
| SCHEMBL5254514 | 0.79 | CTSS (0.53) | CTSSCD74 | |
| SCHEMBL2969272 | 0.79 | KCNK3 (0.59) | CTSSCD74KCNK3 | |
| SCHEMBL2983724 | 0.78 | CTSS (0.47) | CTSSCD74KCNK3 | |
| SCHEMBL2971508 | 0.78 | CTSS (0.60) | CTSSCD74KCNK3 | |
| SCHEMBL2972624 | 0.77 | CTSS (0.55) | CTSSCD74KCNK3 | |
| SCHEMBL2978007 | 0.77 | CTSS (0.63) | CTSSCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315491-B1 | USE OF SUBSTITUTED PYRAZOLES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF ALLERGIES | ORTHO MCNEIL PHARM INC (US) | 2006-08-09 | — | — | EP | disclosed |