Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 15/20 | 0.45 |
| ▸ | WNT1 | P04628 | 6/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | CLK2 | P49760 | 3/20 | 0.42 |
| ▸ | CLK3 | P49761 | 3/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305261 | 0.86 | PIK3CA (0.64) | PIK3CADYRK1AWNT1GSK3BALDH1A1 | |
| SCHEMBL5775896 | 0.81 | RAB9A (0.50) | DYRK1AWNT1GSK3BCLK2CLK3 | |
| SCHEMBL12639902 | 0.79 | HRH4 (0.54) | HRH4PIK3CADYRK1AWNT1GSK3B | |
| SCHEMBL20951481 | 0.79 | PIK3CA (0.68) | HRH4PIK3CADYRK1AWNT1GSK3B | |
| SCHEMBL20967224 | 0.78 | HRH4 (0.52) | HRH4PIK3CADYRK1AWNT1GSK3B | |
| Hydrochloric Acid SCHEMBL20951268 | 0.78 | PIK3CA (0.67) | HRH4PIK3CADYRK1AWNT1GSK3B | |
| SCHEMBL7887377 | 0.78 | KDM4E (0.55) | HRH4PIK3CADYRK1AWNT1GSK3B | |
| SCHEMBL24269753 | 0.77 | HDAC3 (0.50) | HRH4USP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7887400 | 0.76 | DYRK1A (0.59) | DYRK1AWNT1GSK3BCLK2CLK3 | |
| SCHEMBL1516956 | 0.75 | PIK3CA (0.75) | HRH4PIK3CADYRK1AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | HRH4 38/4885PIK3CA 4848/4885DYRK1A 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.