Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780874 | 0.84 | ACP1 (0.45) | MAPK10KMT2AMEN1L3MBTL1ACP1 | |
| SCHEMBL5771541 | 0.82 | KMT2A (0.44) | MAPK10KMT2AMEN1L3MBTL1ACP1 | |
| SCHEMBL5749052 | 0.81 | KMT2A (0.55) | MAPK10KMT2AMEN1L3MBTL1ACP1 | |
| SCHEMBL5771888 | 0.77 | MAPK10 (0.44) | MAPK10KMT2AMEN1L3MBTL1ACP1 | |
| SCHEMBL5774898 | 0.74 | KMT2A (0.46) | MAPK10KMT2AMEN1L3MBTL1ACP1 | |
| SCHEMBL5770706 | 0.72 | KMT2A (0.46) | MAPK10KMT2AMEN1L3MBTL1ACP1 | |
| SCHEMBL5750843 | 0.71 | ALDH1A1 (0.39) | GRM5MAPK10KMT2AMEN1L3MBTL1 | |
| SCHEMBL5748108 | 0.71 | RIOK2 (0.44) | MAPK10KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL5770309 | 0.70 | ALDH1A1 (0.43) | MAPK10KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL5750823 | 0.70 | KDM4E (0.37) | MAPK10KMT2AMEN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |