Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703168 | 0.93 | THRB (0.48) | THRBHSD17B10KMT2AHPGDPTGER4 | |
| SCHEMBL5812811 | 0.91 | THRB (0.46) | THRBHSD17B10HPGDPTGER4HCAR3 | |
| SCHEMBL5781185 | 0.91 | THRB (0.48) | THRBHSD17B10KMT2AHPGDPTGER4 | |
| SCHEMBL5781887 | 0.91 | THRB (0.48) | THRBHSD17B10KMT2AHPGDPTGER4 | |
| SCHEMBL5779114 | 0.90 | THRB (0.47) | THRBHSD17B10KMT2AHPGDPTGER4 | |
| SCHEMBL5782596 | 0.90 | THRB (0.48) | THRBHSD17B10KMT2AHPGDPTGER4 | |
| SCHEMBL5782481 | 0.89 | HSD17B10 (0.47) | THRBHSD17B10KMT2AHPGDPTGER4 | |
| SCHEMBL4702408 | 0.89 | THRB (0.44) | THRBHSD17B10KMT2AHPGDPTGER4 | |
| SCHEMBL5783447 | 0.88 | HPGD (0.46) | THRBHSD17B10KMT2AHPGDPTGER4 | |
| SCHEMBL5783864 | 0.88 | THRB (0.46) | THRBHSD17B10KMT2AHPGDPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194410-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2006-01-18 | — | — | EP | claimed |