Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780037 | 0.92 | PPM1B (0.46) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL24287722 | 0.92 | PPM1B (0.39) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL18562238 | 0.90 | PPM1B (0.38) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL8970208 | 0.88 | PPM1B (0.39) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL30672673 | 0.86 | PPM1B (0.38) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL8969292 | 0.85 | PPM1B (0.37) | PPM1BPTPN1PPP1CCTSHRLMNA | |
| SCHEMBL23780231 | 0.82 | — | — | |
| SCHEMBL8914013 | 0.80 | ALDH1A1 (0.48) | PPM1BPTPN1PPP1CCALDH1A1LMNA | |
| SCHEMBL2705851 | 0.80 | ALDH1A1 (0.48) | PPM1BPTPN1PPP1CCALDH1A1LMNA | |
| SCHEMBL2705849 | 0.80 | ALDH1A1 (0.48) | PPM1BPTPN1PPP1CCALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111582-A1 | AZA-TETRACYCLIC OXAZEPINE INHIBITORS OF KRAS-G12D | GENENTECH, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |
| US-4309436-A | 3'(3,5-Dichlorophenyl)-spiro(3-oxabicycloc[3.1.0]hexane)-6,5'-oxazolidine-2',4'-dione | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |