Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | LDLR | P01130 | 1/20 | 0.43 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 8/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.38 |
| ▸ | WNT1 | P04628 | 2/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22144037 | 0.84 | IDO1 (0.47) | IDO1HPGDSLDLRPCSK9PRMT5 | |
| SCHEMBL5779888 | 0.79 | IDO1 (0.50) | IDO1HPGDSLDLRPCSK9PRMT5 | |
| SCHEMBL1502339 | 0.77 | IDO1 (0.51) | IDO1HPGDSLDLRPCSK9PRMT5 | |
| SCHEMBL5779858 | 0.77 | SMN1; SMN2 (0.55) | IDO1GSK3BDYRK1AWNT1 | |
| SCHEMBL24185698 | 0.76 | IDO1 (0.50) | IDO1HPGDSLDLRPCSK9PRMT5 | |
| Ammonia Solution, Strong SCHEMBL28862527 | 0.76 | IDO1 (0.50) | IDO1HPGDSLDLRPCSK9PRMT5 | |
| SCHEMBL3452742 | 0.76 | IDO1 (0.50) | IDO1HPGDSLDLRPCSK9PRMT5 | |
| SCHEMBL10985317 | 0.76 | IDO1 (0.53) | IDO1HPGDSLDLRPCSK9PRMT5 | |
| SCHEMBL15875301 | 0.76 | IDO1 (0.64) | IDO1HPGDSLDLRPCSK9PRMT5 | |
| SCHEMBL27398874 | 0.76 | IDO1 (0.50) | IDO1HPGDSLDLRPCSK9PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | IDO1 1988/4885HPGDS 741/4885LDLR 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.