Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 7/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.45 |
| ▸ | WNT1 | P04628 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22144037 | 0.78 | IDO1 (0.47) | GSK3BDYRK1AWNT1IDO1 | |
| SCHEMBL5778130 | 0.77 | IDO1 (0.46) | GSK3BDYRK1AWNT1IDO1 | |
| SCHEMBL28181744 | 0.76 | ALDH1A1 (0.51) | SMN1; SMN2HTTL3MBTL1ALDH1A1MAPT | |
| SCHEMBL19706556 | 0.76 | PIK3C3 (0.53) | GSK3BDYRK1AWNT1 | |
| SCHEMBL5344758 | 0.76 | HPGDS (0.53) | GSK3BDYRK1AWNT1IDO1CYP3A4 | |
| SCHEMBL22143828 | 0.75 | IDO1 (0.47) | SMN1; SMN2ALDH1A1GSK3BDYRK1AWNT1 | |
| SCHEMBL22143832 | 0.75 | TAAR1 (0.44) | SMN1; SMN2HTTMEN1KMT2AGSK3B | |
| SCHEMBL10985317 | 0.74 | IDO1 (0.53) | GSK3BDYRK1AWNT1IDO1 | |
| SCHEMBL3818831 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTL3MBTL1ALDH1A1MAPT | |
| SCHEMBL16201493 | 0.73 | GSK3B (0.45) | SMN1; SMN2MAPTMEN1KMT2AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | SMN1; SMN2 2146/4885HTT 3/4885L3MBTL1 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.