Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | APAF1 | O14727 | 2/20 | 0.48 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | S100A4 | P26447 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102781 | 0.82 | MEN1 (0.37) | CDC25BMEN1KMT2AMAOARAB9A | |
| Anthraquinone SCHEMBL8081485 | 0.78 | MEN1 (0.92) | CDC25BMEN1KMT2AMAOARAB9A | |
| Anthraquinone SCHEMBL14943 | 0.75 | MEN1 (1.00) | CDC25BMEN1KMT2AMAOARAB9A | |
| Anthraquinone SCHEMBL29358690 | 0.75 | MEN1 (1.00) | CDC25BMEN1KMT2AMAOARAB9A | |
| Anthraquinone SCHEMBL1901249 | 0.75 | MEN1 (1.00) | CDC25BMEN1KMT2AMAOARAB9A | |
| Anthraquinone SCHEMBL20299926 | 0.72 | MEN1 (0.92) | CDC25BMEN1KMT2AMAOARAB9A | |
| Anthraquinone SCHEMBL10905960 | 0.72 | MEN1 (0.92) | CDC25BMEN1KMT2AMAOARAB9A | |
| Anthraquinone SCHEMBL7205968 | 0.72 | MEN1 (0.92) | CDC25BMEN1KMT2AMAOARAB9A | |
| Anthraquinone SCHEMBL10991985 | 0.72 | MEN1 (0.92) | CDC25BMEN1KMT2AMAOARAB9A | |
| Anthraquinone SCHEMBL6415478 | 0.72 | MEN1 (0.92) | CDC25BMEN1KMT2AMAOARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284307-B2 | Macrocyclic serine protease inhibitors | IDENIX PHARMACEUTICALS LLC (US) | 2016-03-15 | — | — | US | disclosed |
| US-8993595-B2 | Macrocyclic serine protease inhibitors | IDENIX PHARMACEUTICALS, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20130224147-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2013-08-29 | — | — | US | disclosed |
| US-8377962-B2 | Macrocyclic serine protease inhibitors | IDENIX PHARMACEUTICALS, INC. (US) | 2013-02-19 | — | — | US | disclosed |
| EP-2461811-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS USEFUL AGAINST VIRAL INFECTIONS, PARTICULARLY HCV | IDENIX Pharmaceuticals, Inc. (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-2417134-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX Pharmaceuticals, Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20110129443-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| WO-2011017389-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS USEFUL AGAINST VIRAL INFECTIONS, PARTICULARLY HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2011-02-10 | — | — | WO | disclosed |
| WO-2010118078-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20100260710-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | US | disclosed |
| EP-0677791-B1 | Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus having the electrophotographic photosensitive member | CANON KK (JP) | 2000-07-12 | — | — | EP | disclosed |
| EP-0657781-B1 | Electrophotographic photosensitive member, process cartridge including same and electrophotographic apparatus | CANON KK (JP) | 2000-05-03 | — | — | EP | disclosed |
| EP-0656567-B1 | Electrophotographic member, process cartridge and electrophotographic apparatus | CANON KK (JP) | 1999-01-27 | — | — | EP | disclosed |
| US-5629116-A | Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus having the electrophotographic photosensitive member | CANON KABUSHIKI KAISHA (JP) | 1997-05-13 | — | — | US | disclosed |
| US-5622799-A | PHOTOSENSITIVE LAYER CONTAINING DISAZO PIGMENTS | CANON KABUSHIKI KAISHA (JP) | 1997-04-22 | — | — | US | disclosed |
| US-5543257-A | PHOTOSENSITIVE LAYER CONTAINS A SPECIFIC DISAZO PIGMENT HAVING A 2,2'-BIS-1,3-BENZDITHIOLENE-DIYL OR THIOPHENE-DIYL SKELETON | CANON KABUSHIKI KAISHA (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0677791-A2 | Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus having the electrophotographic photosensitive member | CANON KABUSHIKI KAISHA (JP) | 1995-10-18 | — | — | EP | disclosed |
| EP-0657781-A1 | Electrophotographic photosensitive member, process cartridge including same and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 1995-06-14 | — | — | EP | disclosed |
| EP-0656567-A1 | Electrophotographic member, process cartridge and electrophotographic apparatus having the electrophotographic photosensitive member | CANON KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110129443-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | SERPINB1, SPINT2, PRSS1 | CDC25B 1174/4885MEN1 3502/4885KMT2A 4323/4885 |
| US-20130224147-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | SERPINB1, SPINT2, PRSS1 | CDC25B 1174/4885MEN1 3502/4885KMT2A 4323/4885 |
| US-20100260710-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | SERPINB1, SPINT2, PRSS1 | CDC25B 1174/4885MEN1 3502/4885KMT2A 4323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.