Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26618 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL31554744 | 0.96 | CRBN (0.93) | CRBNMAPTOR51E2FKBP5ALDH1A1 | |
| SCHEMBL7459731 | 0.96 | — | — | |
| Bromide SCHEMBL31527773 | 0.96 | — | — | |
| Succinimide SCHEMBL993083 | 0.96 | CRBN (0.93) | CRBNMAPTOR51E2FKBP5ALDH1A1 | |
| SCHEMBL11016133 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL29153064 | 0.96 | CRBN (0.93) | CRBNMAPTOR51E2FKBP5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3244385 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL10590100 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL30727530 | 0.96 | CRBN (0.93) | CRBNMAPTOR51E2FKBP5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423115-A4 | SYNTHESIS AND ANTI-TUMOR ACTIVITY OF NITROGEN SUBSTITUTED THALIDOMIDE ANALOGS | CHILDRENS MEDICAL CENTER (US) | 2006-08-16 | — | — | EP | disclosed |
| EP-1423115-A2 | SYNTHESIS AND ANTI-TUMOR ACTIVITY OF NITROGEN SUBSTITUTED THALIDOMIDE ANALOGS | The Children's Medical Center Corporation (US) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003014315-A2 | SYNTHESIS AND ANTI-TUMOR ACTIVITY OF NITROGEN SUBSTITUTED THALIDOMIDE ANALOGS | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |
| EP-0373911-B1 | Polymer blends with enhanced properties | ROHM & HAAS (US) | 1995-05-24 | — | — | EP | disclosed |
| EP-0373911-A1 | Polymer blends with enhanced properties | ROHM AND HAAS COMPANY (US) | 1990-06-20 | — | — | EP | disclosed |