Succinimide

Succinimide

SCHEMBL993083

O=C1CCC(=O)N1.O=C1CCCC(=O)N1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 6/20 0.93
MAPT P10636 2/20 0.46
OR51E2 Q9H255 1/20 0.45
FKBP5 Q13451 1/20 0.43
ALDH1A1 P00352 3/20 0.41
NPC1 O15118 1/20 0.39
MAPK13 O15264 1/20 0.39
MAPK12 P53778 1/20 0.39
MAPK11 Q15759 1/20 0.39
MAPK14 Q16539 1/20 0.39
CYP2C19 P33261 2/20 0.35
MEN1 O00255 1/20 0.35
TSHR P16473 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
TRIM24 O15164 2/20 0.33
TRIM33 Q9UPN9 2/20 0.33
CA9 Q16790 1/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5778743 0.96 CRBN (1.00) CRBNMAPTOR51E2FKBP5ALDH1A1
SCHEMBL26618 0.96
SCHEMBL7459731 0.93
SCHEMBL7888543 0.93 CRBN (0.80) CRBNMAPTOR51E2FKBP5ALDH1A1
Hydrochloric Acid SCHEMBL31554744 0.93 CRBN (0.93) CRBNMAPTOR51E2FKBP5ALDH1A1
Ammonia Solution, Strong SCHEMBL10590100 0.93
SCHEMBL11016133 0.93
Hydrochloric Acid SCHEMBL3244385 0.93
Bromide SCHEMBL31527773 0.93
Hydrochloric Acid SCHEMBL30727530 0.93 CRBN (0.93) CRBNMAPTOR51E2FKBP5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4032346-A 5-OXO-2-PYRAZOLIN-4-YL-AMINE-CARBODITHIOATE-DITHIOCARBONATE FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US claimed
US-8765850-B2 Polyacetal resin composition and preparation process thereof ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-07-01 US disclosed
EP-2267075-B1 POLYACETAL RESIN COMPOSITION AND METHOD FOR PRODUCING THE SAME ASAHI KASEI CHEMICALS CORP (JP) 2014-01-22 EP disclosed
US-20110015321-A1 POLYACETAL RESIN COMPOSITION AND PREPARATION PROCESS THEREOF ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-01-20 US disclosed
EP-2267075-A1 POLYACETAL RESIN COMPOSITION AND METHOD FOR PRODUCING THE SAME Asahi Kasei Chemicals Corporation (JP) 2010-12-29 EP disclosed