Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5778906

N.c1ccc(-c2ccccc2-c2ccccc2-c2cccc3ccccc23)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
L3MBTL1 Q9Y468 4/20 0.50
TSHR P16473 4/20 0.50
HSD17B10 Q99714 4/20 0.50
MAPT P10636 3/20 0.50
HPGD P15428 3/20 0.50
MAPK1 P28482 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
KDM4E B2RXH2 2/20 0.50
ATM Q13315 2/20 0.50
TP53 P04637 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TNF P01375 1/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
MPI P34949 1/20 0.48
CA12 O43570 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL1552163 1.00 ALDH1A1 (0.50) ALDH1A1L3MBTL1TSHRHSD17B10MAPT
SCHEMBL867854 0.98 TNF (0.52) ALDH1A1L3MBTL1TSHRHSD17B10MAPT
SCHEMBL29732781 0.98 TNF (0.52) ALDH1A1L3MBTL1TSHRHSD17B10MAPT
SCHEMBL29463735 0.98 TNF (0.52) ALDH1A1L3MBTL1TSHRHSD17B10MAPT
SCHEMBL623148 0.98 TNF (0.52) ALDH1A1L3MBTL1TSHRHSD17B10MAPT
SCHEMBL27664395 0.95 ALDH1A1 (0.50) ALDH1A1L3MBTL1TSHRHSD17B10MAPT
SCHEMBL9313726 0.95 ALDH1A1 (0.50) ALDH1A1L3MBTL1TSHRHSD17B10MAPT
Hydrogen Sulfide SCHEMBL27664397 0.95 ALDH1A1 (0.50) ALDH1A1L3MBTL1TSHRHSD17B10MAPT
SCHEMBL28364735 0.93 CA12 (0.49) ALDH1A1L3MBTL1TSHRHSD17B10MAPT
Water SCHEMBL27984347 0.93 ALDH1A1 (0.49) ALDH1A1L3MBTL1TSHRHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1499624-A4 ELECTROLUMINESCENT MATERIALS UNIV HONG KONG (CN) 2006-05-03 EP disclosed
EP-1499624-A1 ELECTROLUMINESCENT MATERIALS The University of Hong Kong (CN) 2005-01-26 EP disclosed
WO-2003093283-A1 ELECTROLUMINESCENT MATERIALS THE UNIVERSITY OF HONG KONG (CN) 2003-11-13 WO disclosed