Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.44 |
| ▸ | BRAF | P15056 | 12/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778687 | 0.89 | MAPK14 (0.43) | MAPK14BRAFLYNMAPK9GSK3A | |
| SCHEMBL5777788 | 0.89 | BRAF (0.45) | MAPK14BRAF | |
| SCHEMBL5777792 | 0.87 | MAPK14 (0.46) | MAPK14BRAFLYNMAPK9GSK3A | |
| SCHEMBL5777714 | 0.86 | MAPK14 (0.44) | MAPK14BRAFLYNMAPK9 | |
| SCHEMBL5779497 | 0.83 | BRAF (0.43) | MAPK14BRAF | |
| SCHEMBL4483684 | 0.82 | MAPK14 (0.49) | MAPK14BRAFLYNMAPK9MEN1 | |
| SCHEMBL5778016 | 0.81 | BRAF (0.43) | MAPK14BRAF | |
| SCHEMBL5776997 | 0.81 | MAPK14 (0.42) | MAPK14BRAFLYNMAPK9 | |
| SCHEMBL5779375 | 0.80 | BRAF (0.36) | MAPK14BRAFMEN1ALDH1A1KMT2A | |
| SCHEMBL5777487 | 0.80 | BRAF (0.43) | MAPK14BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567507-B1 | 1,2,3- TRIAZOLE AMIDE DERIVATIVES AS CYTOKINE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (US) | 2006-06-14 | — | — | EP | claimed |