Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.69 |
| ▸ | CTPS1 | P17812 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266527 | 0.83 | ALB (0.83) | ALBMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL9266539 | 0.83 | ALB (0.83) | ALBMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL9262889 | 0.81 | ALB (1.00) | ALBMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL9262876 | 0.81 | ALB (1.00) | ALBMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL5780400 | 0.81 | ALB (0.53) | ALBCTPS1MAPTMEN1ALDH1A1 | |
| SCHEMBL9263855 | 0.79 | ALB (0.74) | ALBMAPTMEN1ALDH1A1TP53 | |
| Acetic Acid SCHEMBL9263847 | 0.79 | ALB (0.75) | ALBMAPTMEN1ALDH1A1TP53 | |
| Acetic Acid SCHEMBL9263859 | 0.79 | ALB (0.75) | ALBMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL9264563 | 0.78 | ALB (0.71) | ALBCTPS1MAPTMEN1ALDH1A1 | |
| SCHEMBL9264552 | 0.78 | ALB (0.71) | ALBCTPS1MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |