Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834084 | 0.73 | HRH4 (0.46) | CYP1A2KDM4EHTR3AL3MBTL1NR1H4 | |
| SCHEMBL3076096 | 0.72 | L3MBTL1 (0.51) | CYP1A2KDM4ETDP1CYP2A6PDPK1 | |
| SCHEMBL22288174 | 0.72 | L3MBTL1 (0.56) | CYP1A2KDM4ETDP1CYP2A6PDPK1 | |
| SCHEMBL5241881 | 0.71 | BCHE (0.45) | CYP1A2KDM4ECYP2A6PDPK1CHEK1 | |
| SCHEMBL1536419 | 0.71 | CYP1A2 (0.47) | CYP1A2KDM4ETDP1CYP2A6PDPK1 | |
| SCHEMBL22288137 | 0.70 | L3MBTL1 (0.58) | CYP1A2KDM4ETDP1CYP2A6PDPK1 | |
| SCHEMBL20623030 | 0.70 | L3MBTL1 (0.58) | CYP1A2KDM4ETDP1CYP2A6PDPK1 | |
| SCHEMBL30452394 | 0.70 | L3MBTL1 (0.58) | CYP1A2KDM4ETDP1CYP2A6PDPK1 | |
| Hydrochloric Acid SCHEMBL3880186 | 0.70 | BCHE (0.44) | CYP1A2KDM4ECYP2A6PDPK1HTR3A | |
| SCHEMBL12533933 | 0.68 | CYP1A2 (0.47) | CYP1A2KDM4ETDP1CYP2A6PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |