Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500364 | 0.82 | FDPS (0.45) | FDPSSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL8292151 | 0.79 | CA12 (0.49) | CYP1A2L3MBTL1KMT2AALDH1A1SYK | |
| SCHEMBL5779127 | 0.79 | PTPRB (0.49) | SMN1; SMN2NPC1RAB9ALMNATSHR | |
| SCHEMBL4678395 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AL3MBTL1KMT2A | |
| SCHEMBL29611056 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AL3MBTL1KMT2A | |
| SCHEMBL30903939 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ACYP1A2L3MBTL1 | |
| SCHEMBL16255974 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ACYP1A2L3MBTL1 | |
| SCHEMBL30992257 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AL3MBTL1KMT2A | |
| SCHEMBL4424813 | 0.74 | MEN1 (0.52) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL29883532 | 0.74 | CA1 (0.44) | SMN1; SMN2NPC1RAB9ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293297-A1 | Cyanofluoropyrrolidine derviative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1627870-A1 | CYANOFLUOROPYRROLIDINE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293297-A1 | Cyanofluoropyrrolidine derviative | DPP4, DPP3, NPY4R | FDPS 2502/4885SMN1; SMN2 3375/4885NPC1 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.