Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784009 | 0.88 | F10 (0.39) | F10ACHEKMT2AMEN1NPC1 | |
| SCHEMBL5780091 | 0.88 | F10 (0.48) | F10ACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL5781766 | 0.85 | F10 (0.50) | F10ACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL5781951 | 0.84 | F10 (0.51) | F10ACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL5779457 | 0.83 | F10 (0.50) | F10ACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL5779884 | 0.83 | F10 (0.40) | F10KMT2AMEN1NPC1RAB9A | |
| SCHEMBL5783337 | 0.83 | F10 (0.43) | F10KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6402784 | 0.83 | F10 (0.52) | F10ACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL3381035 | 0.82 | F10 (0.51) | F10ACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL6631939 | 0.82 | F10 (0.45) | F10ACHEKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408962-B1 | SUBSTITUTED ISOINDOLES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-03-15 | — | — | EP | disclosed |