Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.33 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5783337 | 0.88 | F10 (0.43) | F10SMN1; SMN2ALDH1A1HPGDACKR3 | |
| SCHEMBL3381006 | 0.83 | F10 (0.45) | F10SMN1; SMN2ALDH1A1HPGDACKR3 | |
| SCHEMBL5779487 | 0.83 | F10 (0.45) | F10SMN1; SMN2ALDH1A1HPGDACKR3 | |
| SCHEMBL6404276 | 0.82 | F10 (0.43) | F10SMN1; SMN2ALDH1A1HPGDACKR3 | |
| SCHEMBL3377662 | 0.81 | HPGD (0.44) | F10SMN1; SMN2ALDH1A1HPGDACKR3 | |
| SCHEMBL3979217 | 0.78 | HPGD (0.40) | F10SMN1; SMN2ALDH1A1HPGDACKR3 | |
| SCHEMBL5780260 | 0.78 | HPGD (0.41) | F10SMN1; SMN2ALDH1A1HPGDACKR3 | |
| SCHEMBL8229731 | 0.75 | F10 (0.39) | F10SMN1; SMN2ALDH1A1HPGDACKR3 | |
| SCHEMBL5784009 | 0.73 | F10 (0.39) | F10SMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL6653375 | 0.71 | F10 (0.37) | F10SMN1; SMN2ALDH1A1HPGDACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408962-B1 | SUBSTITUTED ISOINDOLES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-03-15 | — | — | EP | disclosed |