Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.61 |
| ▸ | TTR | P02766 | 5/20 | 0.48 |
| ▸ | UNG | P13051 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27569880 | 0.87 | ALB (0.57) | ALBHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL5780106 | 0.87 | ALB (0.57) | ALBHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL28748039 | 0.85 | ALB (0.54) | ALBNR1H4 | |
| SCHEMBL5774563 | 0.82 | ALB (0.69) | ALBHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL8304425 | 0.82 | ALB (0.52) | ALBUNGHDAC1HDAC6HDAC3 | |
| SCHEMBL8304428 | 0.82 | ALB (0.52) | ALBUNGHDAC1HDAC6HDAC3 | |
| SCHEMBL5775275 | 0.82 | ALB (0.52) | ALBFBP1 | |
| SCHEMBL7466155 | 0.80 | TTR (0.48) | ALBTTRUNGFBP1P4HB | |
| SCHEMBL7466164 | 0.80 | TTR (0.48) | ALBTTRUNGFBP1P4HB | |
| SCHEMBL9641854 | 0.80 | ALB (0.49) | ALBHDAC1HDAC6NR1H4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-0287471-B1 | CARBOXYSTYRENE DERIVATIVES AND DRUGS CONTAINING THEM AS EFFECTIVE INGREDIENTS | MITSUBISHI KASEI CORPORATION (JP) | 1992-09-09 | — | — | EP | disclosed |
| US-4925861-A | LEUKOTRIENE ANTAGONISTS, PHOSPHOLIPASE INHIBITORS | MITSUBISHI KASEI CORPORATION (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0287471-A2 | Carboxystyrene derivatives and drugs containing them as effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1988-10-19 | — | — | EP | disclosed |