Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.51 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30231219 | 0.90 | CALCRL (0.58) | CALCRLRAMP1 | |
| SCHEMBL4593640 | 0.90 | CALCRL (0.58) | CALCRLRAMP1 | |
| SCHEMBL27571685 | 0.86 | CALCRL (0.51) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3960086 | 0.85 | CALCRL (0.55) | CALCRLRAMP1 | |
| SCHEMBL19874018 | 0.84 | CALCRL (0.54) | CALCRLRAMP1 | |
| SCHEMBL14401025 | 0.83 | CALCRL (0.53) | CALCRLRAMP1 | |
| SCHEMBL2087424 | 0.81 | CALCRL (0.55) | CALCRLRAMP1 | |
| SCHEMBL29872287 | 0.80 | CALCRL (0.52) | CALCRLRAMP1 | |
| SCHEMBL13655717 | 0.80 | CALCRL (0.52) | CALCRLRAMP1 | |
| SCHEMBL2165841 | 0.80 | CALCRL (0.52) | CALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1722792-A1 | SELECTED CGRP-ANTAGONISTS, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2006-11-22 | — | — | EP | claimed |
| WO-2005084672-A1 | SELECTED CGRP-ANTAGONISTS, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-09-15 | — | — | WO | claimed |
| CN-1414960-A | Substituted piperidines, medicaments containing these compounds, and methods for production thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-04-30 | — | — | CN | disclosed |