Dipyridyl

Dipyridyl

SCHEMBL57801

OBO.c1ccc(-c2ccccn2)nc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.78
LMNA P02545 3/20 0.78
CCR1 P32246 3/20 0.78
CCR5 P51681 3/20 0.78
CCR8 P51685 3/20 0.78
P4HTM Q9NXG6 2/20 0.78
CYP1A2 P05177 1/20 0.78
POLB P06746 1/20 0.78
METAP1 P53582 1/20 0.78
BLM P54132 1/20 0.78
HIF1A Q16665 1/20 0.78
DOHH Q9BU89 1/20 0.78
NPC1 O15118 6/20 0.64
RAB9A P51151 5/20 0.64
TP53 P04637 4/20 0.64
ALOX15 P16050 3/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
L3MBTL1 Q9Y468 3/20 0.64
HTT P42858 2/20 0.64
TDP1 Q9NUW8 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL27651116 0.88 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29907716 0.88 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL5922 0.88 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29351528 0.88 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3711450 0.88 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL183651 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL9644480 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL16026844 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL497901 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL6795069 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011053247-A1 METHOD FOR THE DETECTION OF AN ANALYTE BY SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-05-05 WO claimed
EP-3901235-B1 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC IRELAND LTD (IE) 2023-11-15 EP disclosed
EP-3211057-B2 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC IRELAND LTD (IE) 2022-11-02 EP disclosed
US-20220344601-A1 Organic Electroluminescent Devices and Metal Complex Compounds UDC IRELAND LTD (IE) 2022-10-27 US disclosed
US-11393989-B2 Organic electroluminescent devices and metal complex compounds UDC IRELAND LIMITED (IE) 2022-07-19 US disclosed
EP-3901235-A1 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC Ireland Limited (IE) 2021-10-27 EP disclosed
EP-3623444-B1 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC IRELAND LTD (IE) 2021-05-26 EP disclosed
EP-3623444-A1 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC Ireland Limited (IE) 2020-03-18 EP disclosed
US-20190355918-A1 Organic Electroluminescent Devices and Metal Complex Compounds UDC IRELAND LTD (IE) 2019-11-21 US disclosed
US-10396299-B2 Organic electroluminescent devices and metal complex compounds UDC IRELAND LIMITED (IE) 2019-08-27 US disclosed
US-20060182992-A1 Platinum complex of 6,6'-bis(2-methoxyphenyl)-2,2'-bipyridyl; complexes having a tridentate- or higher polydentate-chain structure ligand; durability; red, green, blue color purity; short wavelength; excellent in both luminous characteristics; displays; brightness; light sources UDC IRELAND LIMITED (IE) 2006-08-17 US disclosed
US-6682938-B1 USING COMPOUND HAVING SUBSTRATE-RECOGNITION COMPONENT, FLUORESCENCE ?SWITCH? MEDIATED BY SUBSTRATE RECOGNITION EVENT, AND FLUOROPHORE IN MOLECULE IN IMPLANTABLE SYSTEMS FOR CONTINUOUS TRANSDERMAL MONITORING OF BLOOD GLUCOSE LEVELS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-01-27 US disclosed
US-6673625-B2 NAPTHALIMIDE BORONATE DERIVATIVES AND SUBSTITUTED CHLOROBENZOPHENOXAZINONE BORONATE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-01-06 US disclosed
WO-2001075450-A9 FLUORESCENT LIFETIME ASSAYS FOR NON-INVASIVE QUANTIFICATION OF ANALYTES UNIV CALIFORNIA (US) 2002-12-19 WO disclosed
EP-1214596-A1 GLUCOSE SENSING MOLECULES HAVING SELECTED FLUORESCENT PROPERTIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2002-06-19 EP disclosed
US-20020043651-A1 Fluorescent lifetime assays for non-invasive quantification of analytes such as glucose ENERGY, U.S. DEPARTMENT OF 2002-04-18 US disclosed
US-20020010279-A1 Saccharide sensing molecules having enhanced fluorescent properties LAWRENCE LIVERMORE NATIONAL SECURITY LLC 2002-01-24 US disclosed
WO-2001074968-A2 SACCHARIDE SENSING MOLECULES HAVING ENHANCED FLUORESCENT PROPERTIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-10-11 WO disclosed
WO-2001075450-A2 FLUORESCENT LIFETIME ASSAYS FOR NON-INVASIVE QUANTIFICATION OF ANALYTES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-10-11 WO disclosed
WO-2001020334-A1 GLUCOSE SENSING MOLECULES HAVING SELECTED FLUORESCENT PROPERTIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220344601-A1 Organic Electroluminescent Devices and Metal Complex Compounds EPCAM, TPR, L1CAM KDM4E 1698/4885LMNA 2623/4885CCR1 2666/4885
US-20190355918-A1 Organic Electroluminescent Devices and Metal Complex Compounds EPCAM, TPR, L1CAM KDM4E 1698/4885LMNA 2623/4885CCR1 2666/4885
US-20020010279-A1 Saccharide sensing molecules having enhanced fluorescent properties SLC2A1, SLC2A9, SLC2A2 KDM4E 3240/4885LMNA 1541/4885CCR1 2588/4885
US-10396299-B2 Organic electroluminescent devices and metal complex compounds EPCAM, TPR, L1CAM KDM4E 1698/4885LMNA 2623/4885CCR1 2666/4885
US-11393989-B2 Organic electroluminescent devices and metal complex compounds EPCAM, TPR, L1CAM KDM4E 1698/4885LMNA 2623/4885CCR1 2666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.