Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.70 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.65 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.55 |
| ▸ | HTR3B | O95264 | 4/20 | 0.55 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.55 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16695094 | 0.87 | HRH4 (0.74) | HTR3AHRH4HRH3HTR3EHTR3B | |
| SCHEMBL5780238 | 0.85 | HTR3A (0.72) | HTR3AHRH4HRH3HTR3EHTR3B | |
| SCHEMBL29293410 | 0.85 | HTR3A (0.72) | HTR3AHRH4HRH3HTR3EHTR3B | |
| SCHEMBL605050 | 0.83 | HRH4 (1.00) | HTR3AHRH4HRH3HTR3EHTR3B | |
| SCHEMBL4182196 | 0.83 | HTR3A (0.80) | HTR3AHRH4HRH3HTR3EHTR3B | |
| SCHEMBL21154479 | 0.83 | HTR3A (0.68) | HTR3AHRH4HRH3HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL4059444 | 0.81 | HTR3A (0.78) | HTR3AHRH4HRH3HTR3EHTR3B | |
| SCHEMBL13648774 | 0.79 | HRH3 (1.00) | HTR3AHRH4HRH3HTR3EHTR3B | |
| SCHEMBL6371066 | 0.79 | HTR3A (0.68) | HTR3AHRH4HRH3HTR3EHTR3B | |
| SCHEMBL13648823 | 0.79 | HTR3A (0.72) | HTR3AHRH4HRH3HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102216291-A | Carbamate derivatives containing alkyl-heterocycles, preparation and therapeutic use thereof | SANOFI AVENTIS | 2011-10-12 | — | — | CN | disclosed |
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |