Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5783534 | 0.83 | HDAC1 (0.40) | LMNANPC1MAPTHTTKMT2A | |
| SCHEMBL5784019 | 0.83 | — | — | |
| SCHEMBL5781800 | 0.82 | HDAC1 (0.42) | LMNANPC1MAPTHTTKMT2A | |
| SCHEMBL5781421 | 0.79 | F10 (0.42) | LMNANPC1MAPTHTTHPGD | |
| SCHEMBL5778893 | 0.79 | ACHE (0.40) | LMNANPC1MAPTHTTHPGD | |
| SCHEMBL5780260 | 0.78 | HPGD (0.41) | LMNANPC1MAPTHTTHPGD | |
| SCHEMBL5785216 | 0.78 | ACHE (0.40) | MAPTKMT2AMEN1 | |
| SCHEMBL6218160 | 0.78 | CHRM3 (0.40) | — | |
| SCHEMBL5780501 | 0.76 | NR1I2 (0.31) | — | |
| SCHEMBL5784062 | 0.75 | F10 (0.47) | LMNANPC1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408962-B1 | SUBSTITUTED ISOINDOLES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-03-15 | — | — | EP | disclosed |
| EP-1408962-A1 | SUBSTITUTED ISOINDOLES AND THE USE THEREOF | Bayer HealthCare AG (DE) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003007942-A1 | SUBSTITUTED ISOINDOLES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-01-30 | — | — | WO | disclosed |