Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | CCNC | P24863 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687803 | 0.92 | CCNC (0.46) | FFAR4THRATHRBCCNCCDK8 | |
| SCHEMBL3683736 | 0.91 | FFAR4 (0.48) | FFAR4THRATHRBFFAR1CCNC | |
| SCHEMBL3678558 | 0.91 | FFAR4 (0.47) | FFAR4THRATHRBFFAR1CCNC | |
| SCHEMBL3684362 | 0.90 | FFAR4 (0.48) | FFAR4THRATHRBFFAR1CCNC | |
| SCHEMBL3684041 | 0.87 | THRA (0.48) | FFAR4THRATHRBFFAR1CCNC | |
| SCHEMBL27699026 | 0.87 | FFAR4 (0.46) | FFAR4THRATHRBFFAR1CCNC | |
| SCHEMBL3680094 | 0.87 | FFAR4 (0.46) | FFAR4THRATHRBFFAR1CCNC | |
| SCHEMBL3684873 | 0.87 | FFAR4 (0.47) | FFAR4THRATHRBFFAR1CCNC | |
| SCHEMBL3683933 | 0.86 | THRA (0.52) | FFAR4THRATHRBFFAR1CCNC | |
| SCHEMBL3685321 | 0.85 | FFAR4 (0.44) | FFAR4THRATHRBFFAR1CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660427-A4 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-1660427-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016862-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-02-24 | — | — | WO | disclosed |