Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 4/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4395974 | 0.78 | ALDH1A1 (0.46) | PARP1PARP10PARP11NISCHALDH1A1 | |
| SCHEMBL4383292 | 0.75 | NISCH (0.70) | NISCH | |
| SCHEMBL143761 | 0.72 | NISCH (0.41) | PARP1PARP10PARP11NISCHNUDT1 | |
| SCHEMBL30839806 | 0.67 | CD44 (0.62) | CD44NPC1ALDH1A1CYP3A4TSHR | |
| SCHEMBL3790203 | 0.67 | CD44 (0.62) | CD44NPC1ALDH1A1CYP3A4TSHR | |
| SCHEMBL11185836 | 0.66 | CD44 (0.38) | PARP1PARP10PARP11NISCHTYMS | |
| Hydrochloric Acid SCHEMBL11680714 | 0.65 | CD44 (0.59) | CD44NPC1ALDH1A1CYP3A4TSHR | |
| SCHEMBL22289770 | 0.63 | CD44 (0.56) | CD44NPC1ALDH1A1CYP3A4TSHR | |
| SCHEMBL10912977 | 0.63 | MAPT (0.64) | PARP1PARP10PARP11NISCHTYMS | |
| SCHEMBL831538 | 0.63 | PARP1 (1.00) | PARP1PARP10PARP11PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417204-B1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2006-01-18 | — | — | EP | disclosed |
| EP-1417204-A1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. du Pont de Nemours and Company (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003016304-A1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |