Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006636 | 0.83 | BCHE (0.46) | BCHEACHETAAR1ALDH1A1KDM4E | |
| SCHEMBL12413219 | 0.81 | MAPT (0.58) | MAPTKMT2AMEN1BCHEACHE | |
| SCHEMBL102928 | 0.78 | TSHR (0.42) | MAPTBCHEALDH1A1KDM4ECYP2D6 | |
| Ammonia Solution, Strong SCHEMBL4465336 | 0.77 | TSHR (0.41) | MAPTBCHEALDH1A1KDM4ECYP2D6 | |
| SCHEMBL189440 | 0.74 | MAPT (0.60) | MAPTKMT2AMEN1NR1D1NR1H3 | |
| Water SCHEMBL20912805 | 0.72 | MAPT (0.58) | MAPTKMT2AMEN1NR1D1NR1H3 | |
| Bromide SCHEMBL20912804 | 0.72 | MAPT (0.58) | MAPTKMT2AMEN1NR1D1NR1H3 | |
| SCHEMBL20175936 | 0.70 | MAPT (0.43) | MAPTKMT2AMEN1BCHEACHE | |
| SCHEMBL2006769 | 0.70 | POLB (0.47) | KMT2AMEN1ALDH1A1HPGDSLC6A4 | |
| SCHEMBL12677859 | 0.69 | MAPT (0.70) | MAPTKMT2AMEN1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |