Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4465336 | 0.98 | TSHR (0.41) | TSHRMAPK1ALDH1A1CNR2MGLL | |
| SCHEMBL14673301 | 0.87 | CNR2 (0.44) | TSHRMAPK1ALDH1A1CNR2MGLL | |
| SCHEMBL6551944 | 0.85 | ALDH1A1 (0.40) | TSHRMAPK1ALDH1A1CNR2MGLL | |
| SCHEMBL6644202 | 0.85 | TSHR (0.50) | TSHRMAPK1ALDH1A1CNR2MGLL | |
| SCHEMBL3029785 | 0.85 | TSHR (0.50) | TSHRMAPK1ALDH1A1CNR2MGLL | |
| SCHEMBL10711575 | 0.85 | TSHR (0.50) | TSHRMAPK1ALDH1A1CNR2MGLL | |
| SCHEMBL19064329 | 0.85 | TSHR (0.50) | TSHRMAPK1ALDH1A1CNR2MGLL | |
| SCHEMBL9653111 | 0.83 | TAAR1 (0.44) | AOC3BCHEL3MBTL1MCHR1 | |
| SCHEMBL1796186 | 0.83 | APLNR (0.44) | ALDH1A1AOC3KDM4EMAPT | |
| SCHEMBL6982347 | 0.83 | PYCR1 (0.42) | TSHRMAPK1ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2632 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558489-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-05-28 | — | — | EP | claimed |
| CN-119585248-A | Heteroaryl derivatives as DDR inhibitors | 奇斯药制品公司 | 2025-03-07 | — | — | CN | claimed |
| US-20240425482-A1 | PYRROLIDINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-26 | — | — | US | claimed |
| EP-4419516-A1 | PYRROLIDINE DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-08-28 | — | — | EP | claimed |
| CN-118284601-A | Pyrrolidine derivatives as DDR inhibitors | 奇斯药制品公司 | 2024-07-02 | — | — | CN | claimed |
| WO-2024017876-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-01-25 | — | — | WO | claimed |
| WO-2023066834-A1 | PYRROLIDINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-04-27 | — | — | WO | claimed |
| CN-108368121-B | Process for the preparation of imidazo [1,2-a ] pyrrolo [2,3-e ] pyrazines | 艾伯维公司（US） | 2023-01-13 | — | — | CN | claimed |
| CN-115448864-A | Preparation method of 3-fluoro-3- (1-hydroxyethyl) pyrrolidine-1-carboxylic acid tert-butyl ester | 上海方予健康医药科技有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-115433194-A | Synthetic method of hexahydro-3 aH-furan [2,3-c ] pyrrole-3 a-carboxylic acid methyl ester derivative | 上海毕得医药科技股份有限公司 | 2022-12-06 | — | — | CN | claimed |
| US-8536201-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-09-17 | — | — | US | claimed |
| US-20120322833-A1 | Pesticidal Arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-20 | — | — | US | claimed |
| EP-2519499-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2012-11-07 | — | — | EP | claimed |
| US-20120232278-A1 | Insecticidal Aryl Pyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-09-13 | — | — | US | claimed |
| EP-2463265-A2 | Process for the preparation of insecticidal aryl pyrrolidines | Bayer CropScience AG (DE) | 2012-06-13 | — | — | EP | claimed |
| WO-2011080211-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | claimed |
| US-7230119-B2 | Process for the preparation of substituted pyrrolidine derivatives and intermediates | BIOCRYST PHARMACEUTICALS, INC. (US) | 2007-06-12 | — | — | US | claimed |
| US-20060128789-A1 | Process for the preparation of substituted pyrrolidine derivatives and intermediates | BIOCRYST PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | US | claimed |
| US-6313307-B1 | DEBLOCKING, DEPROTECTING; CATALYTIC HYDROGENATION, ALKYLATION; PREPARING MICROBIOCIDES AGAINST STAPHYLOCOCCUS, STREPTOCOCCUS, MYCOBACTERIUM, AND CLOSTRIDIUM | PHARMACIA & UPJOHN COMPANY | 2001-11-06 | — | — | US | claimed |
| US-5618949-A | Process for synthesis of chiral cis- and trans-3-amino-4-substituted pyrrolidine compounds | ABBOTT LABORATORIES (US) | 1997-04-08 | — | — | US | claimed |