Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | PTK2 | Q05397 | 9/20 | 0.54 |
| ▸ | PTK2B | Q14289 | 4/20 | 0.54 |
| ▸ | KIT | P10721 | 7/20 | 0.52 |
| ▸ | FLT3 | P36888 | 7/20 | 0.52 |
| ▸ | ULK1 | O75385 | 3/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | BMX | P51813 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.51 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292631 | 1.00 | GSK3A (0.57) | GSK3AGSK3BPTK2PTK2BKIT | |
| SCHEMBL2526061 | 0.96 | PTK2 (0.57) | GSK3AGSK3BPTK2PTK2BKIT | |
| SCHEMBL579158 | 0.96 | PTK2 (0.57) | GSK3AGSK3BPTK2PTK2BKIT | |
| SCHEMBL10149253 | 0.96 | PTK2 (0.57) | GSK3AGSK3BPTK2PTK2BKIT | |
| SCHEMBL5576857 | 0.87 | ULK1 (0.56) | PTK2PTK2BKITFLT3ULK1 | |
| SCHEMBL5576850 | 0.87 | ULK1 (0.56) | PTK2PTK2BKITFLT3ULK1 | |
| SCHEMBL13808079 | 0.86 | GSK3A (0.62) | GSK3AGSK3BPTK2PTK2BKIT | |
| SCHEMBL15328911 | 0.86 | ULK1 (0.60) | PTK2PTK2BKITFLT3ULK1 | |
| SCHEMBL12235598 | 0.86 | ULK1 (0.60) | PTK2PTK2BKITFLT3ULK1 | |
| SCHEMBL14616066 | 0.86 | ULK1 (0.60) | PTK2PTK2BKITFLT3ULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623887-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-07 | — | — | US | disclosed |
| EP-2027107-B1 | 2, 4 -DIAMINO PYRIMIDINES AS CELL CYCLE KINASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2012-02-15 | — | — | EP | disclosed |
| US-20090163467-A1 | New compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163467-A1 | New compounds | CCNA1, MKI67, CCNT1 | GSK3A 1514/4885GSK3B 1179/4885PTK2 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.