Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5417462 | 0.95 | DPP4 (0.76) | DPP4KCNH2DPP7DPP8 | |
| SCHEMBL5407479 | 0.82 | DPP4 (1.00) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL17275232 | 0.72 | DPP4 (0.55) | DPP4 | |
| SCHEMBL5487719 | 0.71 | DPP4 (0.53) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL1068220 | 0.70 | DPP4 (0.51) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL1068219 | 0.70 | DPP4 (0.51) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL8289171 | 0.70 | DPP4 (0.77) | DPP4KCNH2DPP7DPP8DPP9 | |
| SCHEMBL14646637 | 0.69 | DPP4 (0.57) | DPP4 | |
| SCHEMBL14645771 | 0.69 | DPP4 (0.57) | DPP4 | |
| SCHEMBL14646674 | 0.69 | FKBP1A (0.58) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406622-B1 | DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK & CO INC (US) | 2006-02-22 | — | — | EP | disclosed |