SCHEMBL578145

SCHEMBL578145

CC(C)CCCCCCCCCCCCCCCOC(CO)COCC(CO)OCCCCCCCCCCCCCCCC(C)C

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.40
CNR1 P21554 4/20 0.40
ALDH1A1 P00352 1/20 0.40
LPAR1 Q92633 6/20 0.38
LPAR3 Q9UBY5 6/20 0.38
LPAR2 Q9HBW0 3/20 0.38
USP2 O75604 1/20 0.38
DNM1 Q05193 1/20 0.36
LPAR6 P43657 2/20 0.36
LPAR4 Q99677 2/20 0.36
LPAR5 Q9H1C0 2/20 0.36
TLR2 O60603 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28995140 0.95 USP2 (0.44) CNR2CNR1ALDH1A1LPAR1LPAR3
SCHEMBL10498365 0.90 USP2 (0.49) CNR2CNR1ALDH1A1LPAR1LPAR3
SCHEMBL9781604 0.90 USP2 (0.53) CNR2CNR1ALDH1A1LPAR1LPAR3
SCHEMBL7598357 0.88 CNR2 (0.44) CNR2CNR1ALDH1A1DNM1
SCHEMBL7598483 0.88 CNR2 (0.44) CNR2CNR1ALDH1A1DNM1
SCHEMBL469524 0.84 USP2 (0.50) CNR2CNR1ALDH1A1LPAR1LPAR3
SCHEMBL2309583 0.83 PLA2G2C (0.42) ALDH1A1LPAR1LPAR3TLR2
SCHEMBL2314245 0.83 PLA2G2C (0.42) ALDH1A1LPAR1LPAR3TLR2
SCHEMBL9189445 0.82 CNR2 (0.56) CNR2CNR1ALDH1A1LPAR1LPAR3
SCHEMBL18584920 0.82 USP2 (0.40) CNR2CNR1ALDH1A1LPAR1LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57120508-A None JP disclosed
JP-56039033-A None JP disclosed
US-8912354-B2 Organopolysiloxane and cosmetic containing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-12-16 US disclosed
EP-2418236-B1 Novel organopolysiloxane and cosmetic containing the same SHINETSU CHEMICAL CO (JP) 2012-11-14 EP disclosed
US-20120040931-A1 NOVEL ORGANOPOLYSILOXANE AND COSMETIC CONTAINING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-02-16 US disclosed
EP-2418236-A1 Novel organopolysiloxane and cosmetic containing the same Shin-Etsu Chemical Co., Ltd. (JP) 2012-02-15 EP disclosed
EP-0931539-B1 Cuticle caring method KAO CORP (JP) 2005-10-19 EP disclosed
EP-0781780-B1 Polysaccharide derivative, and preparation process and use thereof KAO CORP (JP) 2002-05-29 EP disclosed
US-6174523-B1 Hair cuticle caring method KAO CORPORATION (JP) 2001-01-16 US disclosed
US-6123934-A AN ANTIBODY TO HAIR OR TO HAIR EXTRACT OBTAINED FROM EGG YOLK OF POULTRY IMMUNIZED WITH HAIR OR HAIR EXTRACT AND LATEX PARTICLES OF A HOMO OR COPOLYMER SELECTED FROM ISOPRENE, (METH)ACRYLAMIDE, ETHYLENE, STYRENE, BUTADIENE AND PROPYLENE KAO CORPORATION (JP) 2000-09-26 US disclosed
EP-0781780-A2 Polysaccharide derivative, and preparation process and use thereof Kao Corporation (JP) 1997-07-02 EP disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 EP disclosed
EP-0542309-B1 Hair care product KAO CORP (JP) 1995-10-11 EP disclosed
EP-0673638-A2 Hair cosmetic composition containing an antibody Kao Corporation (JP) 1995-09-27 EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 WO disclosed
EP-0542309-A1 Hair care product Kao Corporation (JP) 1993-05-19 EP disclosed
EP-0242792-B1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1992-07-22 EP disclosed
US-4634719-A EMULSIFIERS KAO SOAP CO., LTD. (JP) 1987-01-06 US disclosed
JP-S57120508-A STICK-LIKE COSMETIC KAO CORP 1982-07-27 JP disclosed
JP-S5639033-A ALPHA-MONO(METHYL-BRANCHED ALKYL GLYCERYL ETHER AND SKIN COSMETIC CONTAINING THE SAME KAO CORP 1981-04-14 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120040931-A1 NOVEL ORGANOPOLYSILOXANE AND COSMETIC CONTAINING THE SAME F12, FUCA1, H1-0 CNR2 4504/4885CNR1 3590/4885ALDH1A1 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.