Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14895318 | 0.86 | KIF11 (0.33) | KIF11HSP90AA1HSP90AB1 | |
| SCHEMBL5688271 | 0.80 | AR (0.34) | IDO1 | |
| SCHEMBL27719883 | 0.80 | IDO1 (0.36) | IDO1 | |
| SCHEMBL146460 | 0.73 | AR (0.31) | — | |
| SCHEMBL156028 | 0.73 | APOBEC3G (0.31) | — | |
| SCHEMBL1477305 | 0.72 | — | — | |
| SCHEMBL1519797 | 0.72 | AR (0.32) | KIF11 | |
| SCHEMBL21433967 | 0.72 | EPHX2 (0.32) | — | |
| SCHEMBL44837 | 0.72 | IDO1 (0.57) | IDO1 | |
| SCHEMBL29389277 | 0.72 | IDO1 (0.57) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670794-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | Amgen Inc. (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005033105-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2005-04-14 | — | — | WO | disclosed |