Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741865 | 0.84 | DPP4 (0.39) | DPP4DPP8DPP9 | |
| SCHEMBL5739171 | 0.83 | DPP4 (0.40) | DPP4DPP8DPP9 | |
| SCHEMBL5739246 | 0.83 | DPP4 (0.41) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5447544 | 0.81 | DPP4 (0.50) | DPP4DPP8DPP9 | |
| SCHEMBL5458529 | 0.81 | DPP4 (0.43) | DPP4DPP8DPP9 | |
| SCHEMBL5741196 | 0.74 | DPP4 (0.46) | DPP4DPP8DPP9 | |
| SCHEMBL5740124 | 0.73 | DPP4 (0.44) | DPP4DPP8DPP9 | |
| SCHEMBL5739742 | 0.70 | DPP4 (0.42) | DPP4DPP8DPP9 | |
| Isobutane SCHEMBL5782210 | 0.70 | KCNA5 (0.35) | — | |
| SCHEMBL5738844 | 0.69 | DPP4 (0.49) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678138-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Takeda Pharmaceutical Company Limited (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042488-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-12 | — | — | WO | disclosed |