Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5780649 | 0.99 | CYP1A1 (0.52) | CYP1A1CYP1B1MAPTNPC1RAB9A | |
| SCHEMBL5783174 | 0.83 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL5782004 | 0.82 | MAPT (0.52) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5783814 | 0.76 | AR (0.42) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2097189 | 0.75 | CYP1A1 (0.68) | CYP1A1CYP1B1MAPTNPC1RAB9A | |
| SCHEMBL15477792 | 0.75 | CYP1A1 (0.68) | CYP1A1CYP1B1MAPTNPC1RAB9A | |
| SCHEMBL30557661 | 0.75 | CYP1A1 (0.75) | CYP1A1CYP1B1MAPTNPC1RAB9A | |
| SCHEMBL1821573 | 0.75 | CYP1A1 (0.75) | CYP1A1CYP1B1MAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5782911 | 0.75 | AR (0.41) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2097185 | 0.73 | CYP1A1 (0.64) | CYP1A1CYP1B1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636219-B1 | NOVEL THIAZOLYLMETHYL PYRAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF IN DYES FOR KERATIN FIBERS | WELLA AG (DE) | 2006-11-02 | — | — | EP | claimed |
| US-20060183781-A1 | Novel thiazolylmethyl pyrazoles, method for the production thereof, and use thereof in dyes for keratin fibers | WELLA AG (DE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183781-A1 | Novel thiazolylmethyl pyrazoles, method for the production thereof, and use thereof in dyes for keratin fibers | KRT18, CBR3, CDC73 | CYP1A1 123/4885CYP1B1 140/4885MAPT 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.