Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5782004 | 0.99 | MAPT (0.52) | MAPTRAB9AALDH1A1NPC1POLB | |
| SCHEMBL5782556 | 0.86 | LOXL2 (0.41) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5781667 | 0.85 | TAAR1 (0.43) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL5780265 | 0.84 | RAB9A (0.50) | MAPTRAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL5784983 | 0.84 | LMNA (0.50) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL5785031 | 0.84 | MAPT (0.50) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL5785113 | 0.84 | LOXL2 (0.51) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5781236 | 0.83 | MAPT (0.49) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5782285 | 0.83 | RAB9A (0.49) | MAPTRAB9AALDH1A1NPC1MEN1 | |
| Hydrochloric Acid SCHEMBL5782523 | 0.83 | LMNA (0.49) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636219-B1 | NOVEL THIAZOLYLMETHYL PYRAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF IN DYES FOR KERATIN FIBERS | WELLA AG (DE) | 2006-11-02 | — | — | EP | claimed |