Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.58 |
| ▸ | OXTR | P30559 | 10/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3157286 | 0.86 | HTR6 (0.78) | HTR6OXTRALDH1A1KDM4ENPSR1 | |
| SCHEMBL3153033 | 0.81 | HTR6 (0.70) | HTR6OXTR | |
| SCHEMBL5435335 | 0.80 | HTR6 (0.46) | HTR6ALDH1A1USP2 | |
| SCHEMBL3328861 | 0.75 | HTR6 (1.00) | HTR6OXTR | |
| SCHEMBL4394046 | 0.75 | HTR6 (1.00) | HTR6ALDH1A1USP2 | |
| SCHEMBL6051263 | 0.74 | HTR6 (0.43) | HTR6ALDH1A1USP2 | |
| SCHEMBL3157039 | 0.73 | HTR6 (0.80) | HTR6KDM4E | |
| SCHEMBL3142899 | 0.73 | HTR6 (0.69) | HTR6OXTRALDH1A1 | |
| SCHEMBL3147511 | 0.70 | HTR6 (0.81) | HTR6OXTR | |
| SCHEMBL3152456 | 0.70 | HTR6 (0.75) | HTR6OXTRALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-04-26 | — | — | EP | claimed |
| WO-2005014589-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE S.A. (DE) | 2005-02-17 | — | — | WO | claimed |
| EP-1648886-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005014589-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE S.A. (DE) | 2005-02-17 | — | — | WO | disclosed |