⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578550 | 0.82 | — | — | |
| SCHEMBL960629 | 0.80 | MAPT (0.58) | — | |
| SCHEMBL9468203 | 0.78 | MAPT (0.61) | — | |
| SCHEMBL4835234 | 0.78 | MAPT (0.61) | — | |
| SCHEMBL472207 | 0.78 | MAPT (0.61) | — | |
| SCHEMBL1394299 | 0.78 | MAPT (0.61) | — | |
| SCHEMBL472166 | 0.78 | MAPT (0.61) | — | |
| SCHEMBL4834358 | 0.78 | MAPT (0.61) | — | |
| SCHEMBL472200 | 0.78 | MAPT (0.61) | — | |
| SCHEMBL627627 | 0.77 | MAPT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260186-B | VMAT2 inhibitor and preparation method and application thereof | 山东绿叶制药有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-112689509-B | Heterocyclic sulfonamide derivatives and pharmaceutical uses thereof | 梅特恩生物科学有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117700635-A | Dispersing thickener, preparation method and application thereof | 浙江震东新材料有限公司 | 2024-03-15 | — | — | CN | claimed |
| WO-2023178065-A2 | LIPID COMPOUNDS AND LIPID NANOPARTICLES | BROADPHARM INC. (US) | 2023-09-21 | — | — | WO | claimed |
| EP-3880676-B1 | 2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDIN-1-ONE DERIVATIVES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER | PFIZER (US) | 2023-08-02 | — | — | EP | claimed |
| CN-115974713-A | Fluorine-containing compound, preparation method and compound containing fluorine-containing compound | 中国科学技术大学 | 2023-04-18 | — | — | CN | claimed |
| US-20230009549-A1 | BISSULFONATE COMPOUND, PREPARATION METHOD THEREFOR, ELECTROLYTE SOLUTION AND ENERGY STORAGE DEVICE | GUANGZHOU TINCI MATERIALS TECHNOLOGY CO., LTD. (CN) | 2023-01-12 | — | — | US | claimed |
| US-20220411421-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS AND USE THEREOF | CHOU, YU-CHENG (TW) | 2022-12-29 | — | — | US | claimed |
| CN-115073544-A | PARP inhibitor pyrazoloquinine derivative and synthesis method thereof | 上海应用技术大学 | 2022-09-20 | — | — | CN | claimed |
| EP-4015517-A1 | VMAT2 INHIBITOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shandong Luye Pharmaceutical Co., Ltd. (CN) | 2022-06-22 | — | — | EP | claimed |
| US-8962608-B2 | Cycloalkylnitrile pyrazole carboxamides as janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-02-24 | — | — | US | claimed |
| US-20140243309-A1 | CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-08-28 | — | — | US | claimed |
| WO-2014095414-A1 | METHOD FOR THE PLANAR PHOTOALIGNMENT | ROLIC AG (CH) | 2014-06-26 | — | — | WO | claimed |
| EP-1274676-A2 | POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 1,4-QUINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | Pharmacia Corporation (US) | 2003-01-15 | — | — | EP | claimed |
| EP-1268428-A2 | POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 4-PYRIDONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | Pharmacia Corporation (US) | 2003-01-02 | — | — | EP | claimed |
| WO-2001079155-A2 | POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 1,4-QUINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-10-25 | — | — | WO | claimed |
| WO-2001077079-A2 | POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 4-PYRIDONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-10-18 | — | — | WO | claimed |
| EP-0338656-A2 | Polymeric silicone-based materials with high oxygen permeability | BAUSCH & LOMB INCORPORATED (US) | 1989-10-25 | — | — | EP | claimed |
| EP-0316097-A1 | Naphtho(2,1-b)furan derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-17 | — | — | EP | claimed |
| US-4810764-A | CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1989-03-07 | — | — | US | claimed |