SCHEMBL1394299

SCHEMBL1394299

CCCCCCCCCC(F)[C](F)F

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.61
LMNA P02545 1/20 0.46
GPR84 Q9NQS5 4/20 0.41
FDPS P14324 3/20 0.41
SPHK1 Q9NYA1 1/20 0.41
FFAR1 O14842 1/20 0.41
CES2 O00748 1/20 0.41
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
DNM1 Q05193 1/20 0.40
LCK P06239 1/20 0.40
PPARD Q03181 1/20 0.40
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH4 P08319 1/20 0.39
ADH7 P40394 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9468203 1.00 MAPT (0.61) MAPTLMNAGPR84FDPSSPHK1
SCHEMBL472166 1.00 MAPT (0.61) MAPTLMNAGPR84FDPSSPHK1
SCHEMBL472200 1.00 MAPT (0.61) MAPTLMNAGPR84FDPSSPHK1
SCHEMBL472207 1.00 MAPT (0.61) MAPTLMNAGPR84FDPSSPHK1
SCHEMBL4835234 1.00 MAPT (0.61) MAPTLMNAGPR84FDPSSPHK1
SCHEMBL4834358 1.00 MAPT (0.61) MAPTLMNAGPR84FDPSSPHK1
SCHEMBL960629 0.97 MAPT (0.58) MAPTLMNAGPR84FDPSSPHK1
SCHEMBL578550 0.90
SCHEMBL1266499 0.80 MAPT (0.61) MAPTLMNAGPR84FDPSSPHK1
SCHEMBL578491 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974713-A Fluorine-containing compound, preparation method and compound containing fluorine-containing compound 中国科学技术大学 2023-04-18 CN claimed
CN-107209146-B Electrochemical gas sensor and electrolyte for electrochemical gas sensor 德尔格安全股份两合公司 2024-03-12 CN disclosed
WO-2023178065-A2 LIPID COMPOUNDS AND LIPID NANOPARTICLES BROADPHARM INC. (US) 2023-09-21 WO disclosed
CN-115974713-A Fluorine-containing compound, preparation method and compound containing fluorine-containing compound 中国科学技术大学 2023-04-18 CN disclosed
CN-113252759-A Electrochemical gas sensor and electrolyte for electrochemical gas sensor 德尔格安全股份两合公司 2021-08-13 CN disclosed
US-9786450-B2 Membrane switch and object employing same AJINOMOTO CO., INC. (JP) 2017-10-10 US disclosed
US-9464167-B2 Poly α-amino acid and ferroelectric memory element using same AJINOMOTO CO., INC. (JP) 2016-10-11 US disclosed
US-9450174-B2 Piezoelectric element AJINOMOTO CO., INC. (JP) 2016-09-20 US disclosed
US-9206131-B2 Compounds having antiparasitic or anti-infectious activity OREGON HEALTH & SCIENCE UNIVERSITY (US) 2015-12-08 US disclosed
US-20150311012-A1 MEMBRANE SWITCH AND OBJECT EMPLOYING SAME AJINOMOTO CO., INC. (JP) 2015-10-29 US disclosed
US-20140368083-A1 PIEZOELECTRIC ELEMENT AJINOMOTO CO., INC. (JP) 2014-12-18 US disclosed
US-20140138654-A1 POLY ALPHA-AMINO ACID AND FERROELECTRIC MEMORY ELEMENT USING SAME AJINOMOTO CO., INC. (JP) 2014-05-22 US disclosed
EP-2709147-A1 POLY -AMINO ACID AND FERROELECTRIC MEMORY ELEMENT USING SAME Ajinomoto Co., Inc. (JP) 2014-03-19 EP disclosed
US-20140045888-A1 COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2014-02-13 US disclosed
US-8598354-B2 Compounds having antiparasitic or anti-infectious activity UNIVERSITY OF SOUTH FLORIDA (US) 2013-12-03 US disclosed
WO-2012167237-A2 COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY MEDICINES FOR MALARIA VENTURE (CH) 2012-12-06 WO disclosed
US-20120115904-A1 COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY 2012-05-10 US disclosed
US-20120010237-A1 COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY THE GOVERNMENT OF THE UNITED STATES OF AMERICA DBA THE DEPARTMENT OF VETERANS AFFAIRS 2012-01-12 US disclosed
EP-2370411-A2 COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY Oregon Health and Science University (US) 2011-10-05 EP disclosed
WO-2010065905-A2 COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2010-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010237-A1 COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY MASTL, RPS10, CBR3 MAPT 4854/4885LMNA 4352/4885GPR84 2327/4885
US-20140045888-A1 COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY H1-10, RAB10, HDAC10 MAPT 4850/4885LMNA 4506/4885GPR84 2397/4885
US-20120115904-A1 COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY H1-10, RAB10, HDAC10 MAPT 4850/4885LMNA 4515/4885GPR84 2450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.