Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAT2A | P31153 | 2/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3920180 | 0.99 | TSPO (0.58) | TSPOMAPTTP53MAT2APRMT5 | |
| SCHEMBL7003823 | 0.90 | TSPO (0.71) | TSPOMAPTTP53POLB | |
| SCHEMBL3925945 | 0.90 | TSPO (0.57) | TSPOMAPTTP53POLB | |
| SCHEMBL7626011 | 0.89 | TSPO (0.64) | TSPOMAPTTP53 | |
| SCHEMBL3933595 | 0.89 | TSPO (0.59) | TSPOMAPTTP53POLB | |
| SCHEMBL3922481 | 0.89 | TP53 (0.47) | TSPOMAPTTP53POLB | |
| Hydrochloric Acid SCHEMBL3927977 | 0.89 | TSPO (0.58) | TSPOMAPTTP53POLB | |
| SCHEMBL3931680 | 0.87 | TSPO (0.54) | TSPOMAPTTP53POLB | |
| SCHEMBL3932372 | 0.85 | TSPO (0.50) | TSPOMAPTTP53MAT2APOLB | |
| SCHEMBL7003506 | 0.85 | TSPO (0.59) | TSPOMAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458721-B1 | 3-HETEROARYL-3,5-DIHYDRO-4-OXO-4H-PYRIDAZINO [4,5-B]INDOLE-1-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2006-11-22 | — | — | EP | disclosed |