Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | SMO | Q99835 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 3/20 | 0.59 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CTSA | P10619 | 1/20 | 0.52 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14152820 | 0.88 | CNR2 (1.00) | CNR2POLBSMOCNR1RAB9A | |
| SCHEMBL15347911 | 0.86 | POLB (1.00) | CNR2POLBCNR1NFKB1RAB9A | |
| SCHEMBL3048987 | 0.84 | PDE5A (0.64) | CNR2POLBSMOSMN1; SMN2NPSR1 | |
| SCHEMBL13188337 | 0.83 | KAT6A (0.60) | CNR2POLBCNR1KAT6ARAB9A | |
| SCHEMBL3054629 | 0.83 | CNR2 (0.60) | CNR2POLBALDH1A1CTSA | |
| SCHEMBL28790148 | 0.83 | POLB (0.68) | CNR2POLBNFKB1RAB9ANFKB2 | |
| SCHEMBL3044624 | 0.82 | PKM (0.63) | CNR2POLBSMOCNR1KAT6A | |
| SCHEMBL3044625 | 0.82 | PKM (0.63) | CNR2POLBSMOCNR1KAT6A | |
| SCHEMBL2551394 | 0.81 | KAT6A (0.58) | CNR2CNR1KAT6ARAB9AIRAK4 | |
| SCHEMBL13088637 | 0.81 | CNR2 (0.58) | CNR2POLBSMOCNR1KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102333757-B | N-acyl anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2014-11-26 | — | — | CN | disclosed |
| CN-102333757-A | N-acyl anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2012-01-25 | — | — | CN | disclosed |
| EP-1723132-A1 | EP2 RECEPTOR AGONISTS | ASTERAND UK LIMITED (GB) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005080367-A1 | EP2 RECEPTOR AGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2005-09-01 | — | — | WO | disclosed |