SCHEMBL578686

SCHEMBL578686

Cc1ccc([NH])cc1[NH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL654472 0.79
SCHEMBL654475 0.77
SCHEMBL7001043 0.72
SCHEMBL1805666 0.72
SCHEMBL9793496 0.72
SCHEMBL654123 0.72
SCHEMBL1807056 0.72
SCHEMBL655475 0.72
SCHEMBL2995201 0.72
SCHEMBL9144961 0.70 ACHE (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8471031-B2 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2013-06-25 US claimed
EP-2440524-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2012-04-18 EP claimed
US-20120083557-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2012-04-05 US claimed
EP-2035381-B1 PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS BASF SE (DE) 2010-12-29 EP claimed
WO-2010142572-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2010-12-16 WO claimed
US-20100254904-A1 Novel therapeutic delivery systems BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. 2010-10-07 US claimed
US-20100249401-A1 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2010-09-30 US claimed
US-20090318592-A1 Process for the Synthesis of Amine Ethers CIBA CORPORATION (US) 2009-12-24 US claimed
EP-2035381-A1 PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS Ciba Holding Inc. (CH) 2009-03-18 EP claimed
EP-1943236-A2 PROCESS FOR THE SYNTHESIS OF AMINE ETHERS Ciba Holding Inc. (CH) 2008-07-16 EP claimed
EP-0981333-A1 NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS IMARX PHARMACEUTICAL CORP. (US) 2000-03-01 EP claimed
US-5853752-A Methods of preparing gas and gaseous precursor-filled microspheres IMARX PHARMACEUTICAL CORP. (US) 1998-12-29 US claimed
WO-1998051284-A1 NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS IMARX PHARMACEUTICAL CORP. (US) 1998-11-19 WO claimed
WO-1998051282-A1 SOLID POROUS MATRICES AND METHODS OF MAKING AND USING THE SAME IMARX PHARMACEUTICAL CORP. (US) 1998-11-19 WO claimed
EP-0802788-A4 NOVEL THERAPEUTIC DELIVERY SYSTEMS UNGER EVAN C (US) 1998-09-09 EP claimed
EP-0712293-A4 METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES UNGER EVAN C (US) 1998-05-06 EP claimed
EP-0802788-A1 NOVEL THERAPEUTIC DELIVERY SYSTEMS UNGER, Evan C (US) 1997-10-29 EP claimed
EP-0712293-A1 METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES UNGER, Evan C (US) 1996-05-22 EP claimed
WO-1994028780-A2 METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES UNGER EVAN C (US) 1994-12-22 WO claimed
WO-1994028874-A1 NOVEL THERAPEUTIC DELIVERY SYSTEMS UNGER EVAN C (US) 1994-12-22 WO claimed