Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.64 |
| ▸ | ACP1 | P24666 | 10/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.62 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PTPRF | P10586 | 2/20 | 0.53 |
| ▸ | PTPRB | P23467 | 2/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455170 | 1.00 | PTPN1 (0.64) | PTPN1ACP1ENPP2PTPN2CTDSP1 | |
| SCHEMBL5461748 | 0.89 | ENPP2 (0.77) | PTPN1ACP1ENPP2PTPN2PKM | |
| SCHEMBL5461751 | 0.89 | ENPP2 (0.77) | PTPN1ACP1ENPP2PTPN2PKM | |
| SCHEMBL5468711 | 0.89 | ENPP2 (0.54) | PTPN1ACP1ENPP2PTPN2TDP1 | |
| SCHEMBL5468714 | 0.89 | ENPP2 (0.54) | PTPN1ACP1ENPP2PTPN2TDP1 | |
| SCHEMBL5460000 | 0.88 | PTPN1 (0.51) | PTPN1ACP1ENPP2PTPN2PKM | |
| SCHEMBL5460002 | 0.88 | PTPN1 (0.51) | PTPN1ACP1ENPP2PTPN2PKM | |
| SCHEMBL5464100 | 0.83 | ENPP2 (0.49) | PTPN1ACP1ENPP2PTPN2 | |
| SCHEMBL5464096 | 0.83 | ENPP2 (0.49) | PTPN1ACP1ENPP2PTPN2 | |
| SCHEMBL5470534 | 0.83 | ENPP2 (0.55) | PTPN1ACP1ENPP2PTPN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |