⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27949708 | 0.81 | — | — | |
| SCHEMBL1368828 | 0.79 | KIF11 (0.60) | — | |
| SCHEMBL29793056 | 0.79 | KIF11 (0.60) | — | |
| SCHEMBL5266703 | 0.76 | — | — | |
| SCHEMBL238813 | 0.75 | — | — | |
| SCHEMBL22113986 | 0.75 | — | — | |
| SCHEMBL115502 | 0.75 | — | — | |
| SCHEMBL4674694 | 0.75 | — | — | |
| SCHEMBL14833557 | 0.75 | — | — | |
| SCHEMBL1013700 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248426-B | Heterocyclic triarylamine compound and organic photoelectric device containing same | 浙江华显光电科技有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-113248426-A | Heterocyclic triarylamine compound and organic photoelectric device containing same | 浙江华显光电科技有限公司 | 2021-08-13 | — | — | CN | disclosed |
| US-10660888-B2 | Aminoheteroaryl benzamides as kinase inhibitors | NOVARTIS AG (CH) | 2020-05-26 | — | — | US | disclosed |
| US-20190247392-A1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2019-08-15 | — | — | US | disclosed |
| US-10188649-B2 | Aminoheteroaryl benzamides as kinase inhibitors | NOVARTIS AG (CH) | 2019-01-29 | — | — | US | disclosed |
| EP-3063143-B1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |
| US-20180028532-A1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2018-02-01 | — | — | US | disclosed |
| US-9763937-B2 | Aminoheteroaryl benzamides as kinase inhibitors | NOVARTIS AG (CH) | 2017-09-19 | — | — | US | disclosed |
| US-20170182038-A1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2017-06-29 | — | — | US | disclosed |
| EP-3063143-A1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | Novartis AG (CH) | 2016-09-07 | — | — | EP | disclosed |
| US-8481740-B2 | Imidazo[1,2 a] pyridine-6-carboxamide derivatives, their use for the treatment of colon cancer and their method of manufacture | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2013-07-09 | — | — | US | disclosed |
| CN-102008459-B | Antibacterial agents | BIOTA SCIENT MAN | 2013-05-29 | — | — | CN | disclosed |
| CN-101808994-B | Compounds and methods for kinase modulation, and indications therefor | PLEXXIKON INC | 2013-05-15 | — | — | CN | disclosed |
| CN-103086981-A | New compounds | NOVARTIS AG | 2013-05-08 | — | — | CN | disclosed |
| US-20120101122-A1 | IMIDAZO[1,2 A] PYRIDINE 6 CARBOXAMIDE DERIVATIVES, THEIR USE FOR THE TREATMENT OF COLON CANCER AND THEIR METHOD OF MANUFACTURE | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2012-04-26 | — | — | US | disclosed |
| EP-2417136-A1 | IMIDAZ0Ý1,2-A¨PYRIDINE-6-CARBOXAMIDE DERIVATIVES, THEIR USE FOR THE TREATMENT OF COLON CANCER AND THEIR METHOD OF MANUFACTURE | University Of Witwatersrand, Johannesburg (ZA) | 2012-02-15 | — | — | EP | disclosed |
| CN-101404989-B | Antibacterial agent | PROLYSIS LTD | 2011-10-05 | — | — | CN | disclosed |
| CN-102008459-A | Antibacterial agents | PROLYSIS LTD | 2011-04-13 | — | — | CN | disclosed |
| WO-2010116302-A1 | IMIDAZ0[1,2-A] PYRIDINE-6-CARBOXAMIDE DERIVATIVES, THEIR USE FOR THE TREATMENT OF COLON CANCER AND THEIR METHOD OF MANUFACTURE | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2010-10-14 | — | — | WO | disclosed |
| CN-101404989-A | Antibacterial agent | PROLYSIS LTD (GB) | 2009-04-08 | — | — | CN | disclosed |