Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5787549 | 1.00 | NLRP3 (0.64) | NLRP3MEN1KMT2ANSD2HSP90AA1 | |
| SCHEMBL5460282 | 0.89 | MEN1 (0.60) | NLRP3MEN1KMT2ANSD2HSP90AA1 | |
| SCHEMBL5460280 | 0.89 | MEN1 (0.60) | NLRP3MEN1KMT2ANSD2HSP90AA1 | |
| SCHEMBL5457570 | 0.84 | MEN1 (0.64) | MEN1KMT2ANSD2HSP90AA1APOBEC3G | |
| SCHEMBL5457567 | 0.84 | MEN1 (0.64) | MEN1KMT2ANSD2HSP90AA1APOBEC3G | |
| SCHEMBL5461454 | 0.84 | MEN1 (0.61) | NLRP3MEN1KMT2ANSD2HSP90AA1 | |
| SCHEMBL5461449 | 0.84 | MEN1 (0.61) | NLRP3MEN1KMT2ANSD2HSP90AA1 | |
| SCHEMBL5468492 | 0.83 | MEN1 (0.59) | MEN1KMT2ANSD2HSP90AA1APOBEC3G | |
| SCHEMBL5468486 | 0.83 | MEN1 (0.59) | MEN1KMT2ANSD2HSP90AA1APOBEC3G | |
| SCHEMBL5464254 | 0.82 | MEN1 (0.48) | NLRP3MEN1KMT2ANSD2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |