Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979776 | 0.84 | MAOB (0.55) | CA12CA1CA2CA4CA6 | |
| SCHEMBL6794186 | 0.79 | ABCG2 (0.53) | LMNAMAOBCYP1A1CYP1B1RAB9A | |
| SCHEMBL6788300 | 0.79 | ABCG2 (0.53) | LMNAMAOBCYP1A1CYP1B1RAB9A | |
| SCHEMBL6788295 | 0.79 | ABCG2 (0.53) | LMNAMAOBCYP1A1CYP1B1RAB9A | |
| SCHEMBL3985729 | 0.78 | AHR (0.59) | MIFLMNAMAOBERN1CYP1A1 | |
| SCHEMBL4460928 | 0.78 | MAOB (0.53) | CA12CA1CA4CA6CA7 | |
| SCHEMBL8889523 | 0.77 | PDE4D (0.61) | LMNAMAOBHPGDALDH1A1MAPT | |
| SCHEMBL30285970 | 0.77 | CSNK2A1 (0.52) | CA12CA1CA4CA6CA7 | |
| Potassium SCHEMBL31668788 | 0.77 | MAOB (0.51) | CA12CA1CA4CA6CA7 | |
| SCHEMBL402416 | 0.75 | CA12 (0.62) | LMNACA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060205751-A1 | Novel compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-14 | — | — | US | claimed |
| EP-1648885-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-04-26 | — | — | EP | claimed |
| WO-2005009993-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-03 | — | — | WO | claimed |
| US-20060205751-A1 | Novel compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-14 | — | — | US | disclosed |
| EP-1648885-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005009993-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-03 | — | — | WO | disclosed |
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205751-A1 | Novel compounds | KCNN2, KCNN3, KCNN1 | MIF 4768/4885LMNA 2299/4885CA12 1996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.