Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195402 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL2853698 | 0.79 | SLC7A5 (0.39) | ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL2855141 | 0.77 | TSHR (0.41) | ALDH1A1TSHRHSD17B10TDP1GRIK1 | |
| SCHEMBL5813287 | 0.77 | TSHR (0.41) | ALDH1A1TSHRHSD17B10TDP1GRIK1 | |
| SCHEMBL27464717 | 0.77 | TSHR (0.41) | ALDH1A1TSHRHSD17B10TDP1GRIK1 | |
| SCHEMBL1236572 | 0.77 | — | — | |
| SCHEMBL27081721 | 0.77 | — | — | |
| SCHEMBL2697635 | 0.77 | — | — | |
| SCHEMBL2699709 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL2697637 | 0.76 | TSHR (0.40) | ALDH1A1TSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685092-A2 | ASYMMETRIC REDUCTIVE AMINATION OF KETO ACID DERIVATIVES FOR PRODUCING AMINO ACID DERIVATIVES | Takasago International Corporation (JP) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005028419-A2 | ASYMMETRIC REDUCTIVE AMINATION OF KETO ACID DERIVATIVES FOR PRODUCING AMINO ACID DERIVATIVES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-03-31 | — | — | WO | disclosed |